6F6Z

Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidylate synthase	polymer	307	35001.0	2	UniProt (P07607) Pfam (PF00303)	Mus musculus (House Mouse)	TSase
2	C, E (A, B)	2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate)	non-polymer		323.2	2	Chemie (NOH)
3	D, F (A, B)	(2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid	non-polymer		459.5	2	Chemie (TGQ)
4	G, H (A, B)	water	water		18.0	250	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70002.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1565.3
All*	Total formula weight	71567.3

*Water molecules are not included.