6F4P

Human JMJD5 in complex with MN, NOG and RPS6 (129-144) (complex-1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	JmjC domain-containing protein 5	polymer	255	29474.1	1	UniProt (Q8N371) Pfam (PF13621)	Homo sapiens (Human)	Jumonji domain-containing protein 5,Lysine-specific demethylase 8
2	B (B)	40S ribosomal protein S6	polymer	16	1910.4	1	UniProt (P62753)	Homo sapiens	Phosphoprotein NP33,Small ribosomal subunit protein eS6
3	C (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
4	D (A)	N-OXALYLGLYCINE	non-polymer		147.1	1	Chemie (OGA)
5	E (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
6	F, G (A, B)	water	water		18.0	329	Chemie (HOH)

Sequence modifications

A: 183 - 416 (UniProt: Q8N371)

PDB	External Database	Details
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
Ser 168	-	expression tag
Ser 169	-	expression tag
Gly 170	-	expression tag
Val 171	-	expression tag
Asp 172	-	expression tag
Leu 173	-	expression tag
Gly 174	-	expression tag
Thr 175	-	expression tag
Glu 176	-	expression tag
Asn 177	-	expression tag
Leu 178	-	expression tag
Tyr 179	-	expression tag
Phe 180	-	expression tag
Gln 181	-	expression tag
Ser 182	-	expression tag
Ala 217	Cys 217	engineered mutation
Ala 232	Cys 232	engineered mutation
Ala 295	Cys 295	engineered mutation
Ala 384	Cys 384	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31384.5
Non-Polymers*	Number of molecules	3
	Total formula weight	324.2
All*	Total formula weight	31708.6

*Water molecules are not included.