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6F3D

IRAK4 IN COMPLEX WITH inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BInterleukin-1 receptor-associated kinase 4polymer29533315.72UniProt (Q9NWZ3)
Pfam (PF07714)
In PDB
Homo sapiens (Human)IRAK-4,Renal carcinoma antigen NY-REN-64
2A, BSULFATE IONnon-polymer96.12Chemie (SO4)
3A, B4-[4-[[4-(dimethylamino)cyclohexyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]cyclohexane-1-carboxamidenon-polymer384.52Chemie (CJT)
4waterwater18.0113Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66631.3
Non-Polymers*Number of molecules4
Total formula weight961.2
All*Total formula weight67592.5
*Water molecules are not included.

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PDB entries from 2024-07-17

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