6F06

CATHEPSIN L IN COMPLEX WITH (3S,14E)-8-(azetidin-3-yl)-19-chloro-N-(1-cyanocyclopropyl)-5-oxo-12,17-dioxa-4-azatricyclo[16.2.2.06,11]docosa-1(21),6,8,10,14,18(22),19-heptaene-3-carboxamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cathepsin L1	polymer	220	24191.7	2	UniProt (P07711) Pfam (PF00112)	Homo sapiens (Human)	Cathepsin L,Major excreted protein,MEP
2	C, K (A, B)	(3~{S},14~{E})-8-(azetidin-3-yl)-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide	non-polymer		507.0	2	Chemie (C7T)
3	D, E, F, G, H... (A, B)	ZINC ION	non-polymer		65.4	14	Chemie (ZN)
4	J, T (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	U, V (A, B)	water	water		18.0	98	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48383.4
Non-Polymers*	Number of molecules	18
	Total formula weight	2000.6
All*	Total formula weight	50384.0

*Water molecules are not included.