6EZB
Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | polymer | 327 | 36806.4 | 1 | UniProt (Q9NX74) Pfam (PF01207) | Homo sapiens (Human) | Dihydrouridine synthase 2,Up-regulated in lung cancer protein 8,URLC8,tRNA-dihydrouridine synthase 2-like,hDUS2 |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C, D, E, G (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H (A) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 14 - 333 (UniProt: Q9NX74)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | initiating methionine |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| Lys 305 | Gln 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36806.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 932.7 | |
| All* | Total formula weight | 37739.1 |
