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6EXL

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - folded HTH motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Listeriolysin positive regulatory factor Apolymer23927533.62UniProt (Q4TVQ0)
UniProt (by SIFTS) (P22262)
Listeria monocytogenesListeriolysin positive regulatory protein,Listeriolysin regulatory protein,Pleitrophic regulatory factor A,Positive regulatory factor A,PrfA,Transcriptional regulator
2C, G
(A, B)
[(3~{R})-3-carboxy-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azaniumnon-polymer395.52Chemie (C2Q)
3D, E, H
(A, B)
SODIUM IONnon-polymer23.03Chemie (NA)
4F, I
(A, B)
ISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
5J, K
(A, B)
waterwater18.0302Chemie (HOH)
Sequence modifications
A, B: 1 - 237 (UniProt: Q4TVQ0)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55067.3
Non-Polymers*Number of molecules7
Total formula weight980.2
All*Total formula weight56047.4
*Water molecules are not included.

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PDB entries from 2025-07-30

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