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6EXL

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK206) - folded HTH motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BListeriolysin positive regulatory factor Apolymer23927533.62UniProt (Q4TVQ0)
UniProt (by SIFTS) (P22262)
In PDB
Listeria monocytogenesListeriolysin positive regulatory protein,Listeriolysin regulatory protein,Pleitrophic regulatory factor A,Positive regulatory factor A,PrfA,Transcriptional regulator
2A, B[(3~{R})-3-carboxy-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azaniumnon-polymer395.52Chemie (C2Q)
3A, BSODIUM IONnon-polymer23.03Chemie (NA)
4A, BISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
5waterwater18.0302Chemie (HOH)
Sequence modifications
A, B: 1 - 237 (UniProt: Q4TVQ0)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55067.3
Non-Polymers*Number of molecules7
Total formula weight980.2
All*Total formula weight56047.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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