6EW8
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B-cell lymphoma 6 protein | polymer | 124 | 14344.6 | 1 | UniProt (P41182) Pfam (PF00651) | Homo sapiens (Human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | anilinopyrimidine ligand | non-polymer | 444.9 | 1 | Chemie (C0Q) | |||
| 4 | D (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 6 - 129 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Gln 8 | Cys 8 | conflict |
| Arg 67 | Cys 67 | conflict |
| Asn 84 | Cys 84 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14344.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 480.4 | |
| All* | Total formula weight | 14825.0 |
