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6EV0

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (AC129)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BListeriolysin regulatory proteinpolymer23927457.52UniProt (P22262)
In PDB
Listeria monocytogenes EGD-e
2A, B[(3~{R})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azaniumnon-polymer381.52Chemie (BYK)
3A, BISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
4B[(3~{S})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azaniumnon-polymer381.51Chemie (C8N)
5waterwater18.044Chemie (HOH)
Sequence modifications
A, B: 1 - 237 (UniProt: P22262)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54915.0
Non-Polymers*Number of molecules5
Total formula weight1264.6
All*Total formula weight56179.6
*Water molecules are not included.

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PDB entries from 2024-07-17

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