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6EUU

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK29)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Listeriolysin positive regulatory factor Apolymer23927457.52UniProt (Q4TVQ0)
UniProt (by SIFTS) (P22262)
Listeria monocytogenesListeriolysin positive regulatory protein,Listeriolysin regulatory protein,Pleitrophic regulatory factor A,Positive regulatory factor A,PrfA,Transcriptional regulator
2C, G
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
3D, E, H, I
(A, B)
ISOPROPYL ALCOHOLnon-polymer60.14Chemie (IPA)
4F
(B)
(3~{R})-8-cyclopropyl-5-oxidanylidene-7-(quinolin-3-ylmethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acidnon-polymer378.41Chemie (K29)
5J, K
(A, B)
waterwater18.07Chemie (HOH)
Sequence modifications
A, B: 1 - 237 (UniProt: Q4TVQ0)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54915.0
Non-Polymers*Number of molecules7
Total formula weight664.8
All*Total formula weight55579.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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