6ET4
HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH NOVEL INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (Human) | DHOdehase,Dihydroorotate oxidase |
| 2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | A | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 158.1 | 1 | Chemie (DOR) | |||
| 4 | A | N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide | non-polymer | 376.4 | 1 | Chemie (SDV) | |||
| 5 | A | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 201.3 | 1 | Chemie (DDQ) | |||
| 6 | A | ACETIC ACID | non-polymer | 60.1 | 4 | Chemie (ACY) | |||
| 7 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 8 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 9 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 10 | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2007.2 | |
| All* | Total formula weight | 41863.7 |
