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6EPW

The ATAD2 bromodomain in complex with compound UZH-DU32

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATPase family AAA domain-containing protein 2polymer13015453.51UniProt (Q6PL18)
Pfam (PF00439)
Homo sapiens (Human)AAA nuclear coregulator cancer-associated protein,ANCCA
2B, C
(A)
(2~{R})-~{N}-[5-[3,5-bis(oxidanyl)phenyl]-4-ethanoyl-1,3-thiazol-2-yl]-2-carbamimidamido-propanamidenon-polymer363.42Chemie (BQ8)
3D
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4E
(A)
waterwater18.046Chemie (HOH)
Sequence modifications
A: 981 - 1108 (UniProt: Q6PL18)
PDBExternal DatabaseDetails
Ser 979-expression tag
Met 980-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15453.5
Non-Polymers*Number of molecules3
Total formula weight822.8
All*Total formula weight16276.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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