6ENX
Zebrafish Sirt5 in complex with stalled bicyclic intermediate of inhibitory compound 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 271 | 30053.5 | 1 | UniProt (Q6DHI5) Pfam (PF02146) | Danio rerio (Zebrafish) | Regulatory protein SIR2 homolog 5 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | 4-[(2~{R},3~{a}~{R},5~{R},6~{R},6~{a}~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2-[[(5~{S})-6-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanylidene-1-(propan-2-ylamino)propan-2-yl]amino]-6-oxidanylidene-5-(phenylmethoxycarbonylamino)hexyl]amino]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]butanoic acid | non-polymer | 1179.1 | 1 | Chemie (BJW) | |||
| 5 | E (A) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30053.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1322.6 | |
| All* | Total formula weight | 31376.1 |
