6ELR
Human jak1 kinase domain in complex with compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-Protein Kinase JAK1 | polymer | 301 | 34639.1 | 2 | UniProt (P23458) Pfam (PF07714) In PDB | Homo sapiens (Human) | |
| 2 | A, B | [3-[[5-methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol | non-polymer | 482.6 | 2 | Chemie (BFK) | |||
| 3 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69278.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 988.2 | |
| All* | Total formula weight | 70266.5 |
