6EL3

Structure of Progesterone 5beta-Reductase from Arabidopsis thaliana in complex with NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	44056.0	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
2	B (B)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	44083.0	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
3	C (C)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	44056.0	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
4	D (D)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	44001.9	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
5	E (E)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	44056.0	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
6	F (F)	3-oxo-Delta(4,5)-steroid 5-beta-reductase	polymer	381	43974.8	1	UniProt (Q9STX2) Pfam (PF22917)	Arabidopsis thaliana (Mouse-ear cress)	Delta(4)-3-oxosteroid 5-beta-reductase,Delta-4,5-steroid 5-beta-reductase,At5beta-StR,Progesterone 5-beta-reductase,5beta-POR,Protein VEIN PATTERNING 1
7	G, I, K, M, O... (A, B, C, D, E...)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	6	Chemie (NAP)
8	H, J, L, N, P... (A, B, C, D, E...)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
9	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	2673	Chemie (HOH)

Sequence modifications

A: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

B: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

C: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

D: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

E: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

F: 17 - 388 (UniProt: Q9STX2)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Gln 16	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	264227.6
Non-Polymers*	Number of molecules	12
	Total formula weight	4673.1
All*	Total formula weight	268900.8

*Water molecules are not included.