6EJZ

Tryptophan Repressor TrpR from E.coli variant S88Y with Indole-3-acetic acid as ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Trp operon repressor	polymer	116	13517.4	4	UniProt (B7LEN9) Pfam (PF01371) UniProt (by SIFTS) (P0A881)	Escherichia coli (strain 55989 / EAEC)
2	E, I, M, R, V (A, B, C, D)	1H-INDOL-3-YLACETIC ACID	non-polymer		175.2	5	Chemie (IAC)
3	F, G, H, J, K... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
4	Q (C)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	W, X, Y, Z (A, B, C, D)	water	water		18.0	220	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 108 (UniProt: B7LEN9)

PDB	External Database	Details
Tyr 88	Ser 88	conflict
Leu 109	-	expression tag
Glu 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	54069.5
Non-Polymers*	Number of molecules	18
	Total formula weight	1716.8
All*	Total formula weight	55786.3

*Water molecules are not included.