6EJ7

Human Xylosyltransferase 1 in complex with UDP-xylose and peptide QEEEGAGGGQGG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Xylosyltransferase 1	polymer	751	86122.0	1	UniProt (Q86Y38) Pfam (PF02485) Pfam (PF12529)	Homo sapiens (Human)	Peptide O-xylosyltransferase 1,Xylosyltransferase I,XylT-I
2	B (B)	Protein AMBP	polymer	12	1075.0	1	UniProt (P02760)	Homo sapiens
3	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	D (A)	URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE	non-polymer		536.3	1	Chemie (UDX)
5	E (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	F, G, H, I, J... (A)	PHOSPHATE ION	non-polymer		95.0	9	Chemie (PO4)
7	O, P, Q, R (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
8	S, T (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
9	U, V (A, B)	water	water		18.0	366	Chemie (HOH)

Sequence modifications

A: 232 - 959 (UniProt: Q86Y38)

PDB	External Database	Details
Ala 209	-	expression tag
Pro 210	-	expression tag
Leu 211	-	expression tag
Val 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
Ala 219	-	expression tag
Leu 220	-	expression tag
Asp 221	-	expression tag
Glu 222	-	expression tag
Asn 223	-	expression tag
Leu 224	-	expression tag
Tyr 225	-	expression tag
Phe 226	-	expression tag
Gln 227	-	expression tag
Gly 228	-	expression tag
Ala 229	-	expression tag
Leu 230	-	expression tag
Ala 231	-	expression tag

B: 210 - 221 (UniProt: P02760)

PDB	External Database	Details
Ala 215	Ser 215	engineered mutation
Gly 220	Leu 220	engineered mutation
Gly 221	Val 221	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87197.1
Non-Polymers*	Number of molecules	18
	Total formula weight	2095.7
All*	Total formula weight	89292.8

*Water molecules are not included.