6EIM
Human STK10 bound to GW683134A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase 10 | polymer | 302 | 34124.3 | 2 | UniProt (O94804) Pfam (PF00069) In PDB | Homo sapiens (Human) | Lymphocyte-oriented kinase |
| 2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | A, B | ~{N}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{H}-benzimidazol-2-yl]furan-2-carboxamide | non-polymer | 539.4 | 2 | Chemie (B6E) | |||
| 4 | water | water | 18.0 | 742 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
| Ala 248 | Lys 248 | conflict |
| Ala 251 | Lys 251 | conflict |
| Ala 272 | Lys 272 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68248.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1389.2 | |
| All* | Total formula weight | 69637.8 |
