6EIE
Ras guanine nucleotide exchange factor SOS2 (Rem-cdc25), with surface mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Son of sevenless homolog 2 | polymer | 490 | 57370.7 | 1 | UniProt (Q07890) Pfam (PF00618) Pfam (PF00617) | Homo sapiens (Human) | SOS-2 |
| 2 | B (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 562 - 1047 (UniProt: Q07890)
| PDB | External Database | Details |
|---|---|---|
| Gly 558 | - | expression tag |
| Ala 559 | - | expression tag |
| Met 560 | - | expression tag |
| Ala 561 | - | expression tag |
| Gln 564 | Pro 564 | engineered mutation |
| Tyr 707 | Glu 707 | engineered mutation |
| His 768 | Gln 768 | engineered mutation |
| Ile 769 | Phe 769 | engineered mutation |
| Thr 947 | Lys 947 | engineered mutation |
| Arg 948 | Lys 948 | conflict |
| His 949 | Lys 949 | engineered mutation |
| Pro 1019 | Cys 1019 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57370.7 | |
| All* | Total formula weight | 57370.7 |
