6EI8
Crystal structure of human tRNA-dihydrouridine (20) synthase dsRBD F359A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | polymer | 120 | 13652.6 | 1 | UniProt (Q9NX74) Pfam (PF00035) | Homo sapiens (Human) | Dihydrouridine synthase 2,Up-regulated in lung cancer protein 8,URLC8,tRNA-dihydrouridine synthase 2-like,hDUS2 |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 338 - 450 (UniProt: Q9NX74)
| PDB | External Database | Details |
|---|---|---|
| Met 337 | - | initiating methionine |
| Ala 359 | Phe 359 | engineered mutation |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13652.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 13940.8 |
