6EG0

Crystal structure of Dpr4 Ig1-Ig2 in complex with DIP-Eta Ig1-Ig3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Defective proboscis extension response 4	polymer	220	24741.8	1	UniProt (Q59DX6) Pfam (PF07686) Pfam (PF13927)	Drosophila melanogaster (Fruit fly)	Dpr4, FI04761p
2	B (B)	Dpr-interacting protein eta, isoform B	polymer	314	34983.0	1	UniProt (Q9VMN9) Pfam (PF07679) Pfam (PF13927)	Drosophila melanogaster (Fruit fly)	DIP-Eta, Dpr-interacting protein eta,isoform D
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
4	D (D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
5	E (E)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G42466VF)
6	F (F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	1	In PDB GlyTouCan (G80858MF)
7	G (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
8	H, I (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
9	J (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
10	K, L (B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
11	M, N (A, B)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

A: 32 - 246 (UniProt: Q59DX6)

PDB	External Database	Details
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag

B: 31 - 338 (UniProt: Q9VMN9)

PDB	External Database	Details
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59724.7
Branched	Number of molecules	4
	Total formula weight	3661.4
Non-Polymers*	Number of molecules	6
	Total formula weight	613.6
All*	Total formula weight	63999.7

*Water molecules are not included.