6EF0
Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proteasome subunit alpha type-1 | polymer | 238 | 26801.5 | 1 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 2 | B | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 1 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 3 | C | Proteasome subunit alpha type-3 | polymer | 244 | 27080.5 | 1 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 4 | D | Proteasome subunit alpha type-4 | polymer | 242 | 26993.5 | 1 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 5 | E | Proteasome subunit alpha type-5 | polymer | 249 | 27444.9 | 1 | UniProt (P32379) Pfam (PF00227) Pfam (PF10584) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 6 | F | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 1 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 7 | G | Probable proteasome subunit alpha type-7 | polymer | 246 | 27092.7 | 1 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 8 | H | 26S proteasome regulatory subunit 7 homolog | polymer | 257 | 28597.0 | 1 | UniProt (P33299) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein CIM5,Tat-binding homolog 3 |
| 9 | I | 26S proteasome regulatory subunit 4 homolog | polymer | 271 | 30109.6 | 1 | UniProt (P40327) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Tat-binding homolog 5 |
| 10 | J | 26S proteasome regulatory subunit 8 homolog | polymer | 276 | 30522.6 | 1 | UniProt (Q01939) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein CIM3,Protein SUG1,Tat-binding protein TBY1 |
| 11 | K | 26S proteasome regulatory subunit 6B homolog | polymer | 272 | 30387.7 | 1 | UniProt (P33298) Pfam (PF00004) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Protein YNT1,Tat-binding homolog 2 |
| 12 | L | 26S proteasome subunit RPT4 | polymer | 273 | 30386.9 | 1 | UniProt (P53549) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | 26S protease subunit SUG2,Proteasomal cap subunit |
| 13 | M | 26S proteasome regulatory subunit 6A | polymer | 258 | 28497.5 | 1 | UniProt (P33297) Pfam (PF00004) Pfam (PF17862) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Tat-binding protein homolog 1,TBP-1 |
| 14 | s | model substrate polypeptide | polymer | 12 | 1130.3 | 1 | UniProt (by SIFTS) (P07818) In PDB | Homo sapiens (Human) | |
| 15 | H, L, M | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 16 | I, J, K | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 367870.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2803.1 | |
| All* | Total formula weight | 370673.6 |
