6EBK
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Voltage-gated potassium channel subunit beta-2 | polymer | 333 | 37339.1 | 4 | UniProt (P62483) Pfam (PF00248) | Rattus norvegicus (Rat) | K(+) channel subunit beta-2, Kv-beta-2 |
| 2 | B, D, F, H (B, D, F, H) | Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera | polymer | 513 | 58905.8 | 4 | UniProt (P63142) UniProt (Q63099) Pfam (PF02214) Pfam (PF00520) | Rattus norvegicus (Rat) | RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2,CDRK,Voltage-gated potassium channel subunit Kv2.2,RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2 |
| 3 | I, J, K, L (A, C, E, G) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 37 - 367 (UniProt: P62483)
B, D, F, H: 1 - 266 (UniProt: P63142)
B, D, F, H: 267 - 298 (UniProt: Q63099)
B, D, F, H: 299 - 495 (UniProt: P63142)
| PDB | External Database | Details |
|---|---|---|
| Met 35 | - | expression tag |
| Val 36 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | expression tag |
| Ala -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 15 | Leu 15 | conflict |
| Gln 207 | Asn 207 | conflict |
B, D, F, H: 299 - 495 (UniProt: P63142)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 384979.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2973.6 | |
| All* | Total formula weight | 387953.2 |
