6EB5

Crystal Structure of Human Protocadherin-15 EC2-3 V250N

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Protocadherin-15	polymer	259	29390.7	2	UniProt (Q96QU1) Pfam (PF00028)	Homo sapiens (Human)
2	C, D, E, F, G... (B, A)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
3	I, J (B, A)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

B, A: 122 - 369 (UniProt: Q96QU1)

PDB	External Database	Details
Met 119	-	initiating methionine
Ala 120	-	expression tag
Ser 121	-	expression tag
Asn 250	Val 271	engineered mutation
Leu 370	-	expression tag
Glu 371	-	expression tag
His 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58781.4
Non-Polymers*	Number of molecules	6
	Total formula weight	240.5
All*	Total formula weight	59021.8

*Water molecules are not included.