6EA8
Structure of VACV poxin in pre-reactive state with nonhydrolyzable 2'3' cGAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Protein B2 | polymer | 220 | 24743.2 | 10 | UniProt (Q01225) Pfam (PF04766) | Vaccinia virus WR (VACV) | |
| 2 | K, L (A, F) | (2S,5R,7R,8R,10R,12aR,14R,15R,15aS,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-dihydroxy-2,10-disulfanyloctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione | non-polymer | 706.5 | 2 | Chemie (J2A) | |||
| 3 | M (H) | O-[(1R,2R,3R)-5-{[(S)-{[(2R,3R,4R,5R)-2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydro furan-3-yl]oxy}(sulfanyl)phosphoryl]oxy}-1-(6-amino-9H-purin-9-yl)-1,2-dihydroxypentan-3-yl] dihydrogen (R)-phosphorothioate | non-polymer | 726.6 | 1 | Chemie (J2B) | |||
| 4 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 219 (UniProt: Q01225)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 247432.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 2139.7 | |
| All* | Total formula weight | 249571.9 |
