6E7P

cryo-EM structure of human TRPML1 with PI35P2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Mucolipin-1	polymer	580	65085.0	4	UniProt (Q9GZU1) Pfam (PF21381) Pfam (PF08016) In PDB	Homo sapiens (Human)	ML1,MG-2,Mucolipidin,Transient receptor potential channel mucolipin 1,TRPML1
2	A, B, C, D	(1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)]	non-polymer		750.6	4	Chemie (HZ7)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	260340.0
Non-Polymers*	Number of molecules	4
	Total formula weight	3002.4
All*	Total formula weight	263342.4

*Water molecules are not included.