6E7H
Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus in complex with 3'-GcLN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Hemagglutinin HA1 chain | polymer | 334 | 37855.9 | 3 | UniProt (Q5EP31) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33) In PDB | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | |
2 | B, D, F | Hemagglutinin HA2 chain | polymer | 177 | 20414.5 | 3 | UniProt (Q6DQ18) Pfam (PF00509) In PDB | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | |
3 | G, J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
5 | I | N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 487.4 | 1 | In PDB GlyTouCan (G38557KR) | |||
6 | A, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, C, E: 11 - 333 (UniProt: Q5EP31)
B, D, F: 1 - 174 (UniProt: Q6DQ18)
PDB | External Database | Details |
---|---|---|
Ala 7 | - | expression tag |
Asp 8 | - | expression tag |
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
Ala 161 | Tyr 173 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 175 | - | expression tag |
Gly 176 | - | expression tag |
Arg 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 174811.3 | |
Branched | Number of molecules | 4 |
Total formula weight | 1922.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 177176.4 |