6E7G

Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1 chain	polymer	334	37855.9	3	UniProt (Q5EP31) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33)	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
2	B, D, F (B, D, F)	Hemagglutinin HA2 chain	polymer	177	20414.5	3	UniProt (Q6DQ18) Pfam (PF00509)	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
3	G, H, J (G, H, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	I (I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	K, L (A, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, C, E: 11 - 333 (UniProt: Q5EP31)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Ala 161	Tyr 173	engineered mutation

B, D, F: 1 - 174 (UniProt: Q6DQ18)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	174811.3
Branched	Number of molecules	4
	Total formula weight	1859.7
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	177113.4

*Water molecules are not included.