6E76
Structure of Human Transthyretin Asp38Ala/Thr119Met Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Transthyretin | polymer | 115 | 12640.2 | 2 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (Human) | ATTR,Prealbumin,TBPA |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 124 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ala 38 | Asp 58 | engineered mutation |
| Met 119 | Thr 139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25280.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 398.3 | |
| All* | Total formula weight | 25678.7 |
