6E5V
human mGlu8 receptor amino terminal domain in complex with (S)-3,4-Dicarboxyphenylglycine (DCPG)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Metabotropic glutamate receptor 8 | polymer | 523 | 58832.7 | 2 | UniProt (O00222) Pfam (PF01094) In PDB | Homo sapiens (Human) | mGluR8 |
2 | A, B | 4-[(S)-amino(carboxy)methyl]benzene-1,2-dicarboxylic acid | non-polymer | 239.2 | 2 | Chemie (HVG) | |||
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 508 (UniProt: O00222)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ala 1 | - | expression tag |
Leu 2 | - | expression tag |
- | Gln 29 | deletion |
Ser 246 | Cys 246 | engineered mutation |
Asn 509 | - | expression tag |
Leu 510 | - | expression tag |
Tyr 511 | - | expression tag |
Phe 512 | - | expression tag |
Gln 513 | - | expression tag |
Gly 514 | - | expression tag |
Glu 515 | - | expression tag |
Gly 516 | - | expression tag |
His 517 | - | expression tag |
His 518 | - | expression tag |
His 519 | - | expression tag |
His 520 | - | expression tag |
His 521 | - | expression tag |
His 522 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 117665.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 549.3 | |
All* | Total formula weight | 118214.7 |