6E56

Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (D, A)	Hemagglutinin	polymer	290	31994.0	2	UniProt (P03437) Pfam (PF00509)	Influenza A virus
2	C, D (H, G)	antibody H2214 heavy chain	polymer	253	26955.8	2		Homo sapiens (Human)
3	E, F (I, J)	antibody H2214 light chain, K1642	polymer	215	23577.2	2	UniProt (Q6PIL8) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
4	G (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	H, J (D, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	I, K (D, A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
7	L, M, N, O, P... (D, A, H, G, I...)	water	water		18.0	889	Chemie (HOH)

Sequence modifications

D, A: 37 - 319 (UniProt: P03437)

PDB	External Database	Details
Asp 188	Asn 204	conflict
Gly 320	-	expression tag
Leu 321	-	expression tag
Glu 322	-	expression tag
Val 323	-	expression tag
Leu 324	-	expression tag
Phe 325	-	expression tag
Gln 326	-	expression tag

I, J: 1 - 106 (PDB: 6E56)
I, J: 107 - 215 (UniProt: Q6PIL8)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	165054.0
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	4
	Total formula weight	560.5
All*	Total formula weight	166038.9

*Water molecules are not included.