6E3G
Structure of RORgt in complex with a novel agonist.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nuclear receptor ROR-gamma | polymer | 245 | 28568.1 | 2 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | C, D | co-activator peptide | polymer | 8 | 1023.3 | 2 | UniProt (by SIFTS) (Q15788) In PDB | Homo sapiens | |
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | A, B | (5R)-6-acetyl-2-methoxy-N-{4-[(2-methoxyphenyl)methoxy]phenyl}-5,6,7,8-tetrahydro-1,6-naphthyridine-5-carboxamide | non-polymer | 461.5 | 2 | Chemie (HOJ) | |||
| 5 | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59182.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1047.2 | |
| All* | Total formula weight | 60230.0 |
