6E37
O-GlcNAc Transferase in complex with covalent inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | O-GlcNAc transferase subunit p110 | polymer | 723 | 80974.5 | 1 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) In PDB | Homo sapiens (Human) | O-linked N-acetylglucosamine transferase 110 kDa subunit,OGUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitT |
| 2 | B | TYR-PRO-GLY-GLY-SER-THR-PRO-VAL-SER-SER-ALA-ASN | polymer | 14 | 1398.6 | 1 | UniProt (by SIFTS) (P68400) In PDB | Homo sapiens | |
| 3 | A | (2S,3R,4R,5S,6R)-3-[(2E)-but-2-enoylamino]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) | non-polymer | 649.5 | 1 | Chemie (HQV) | |||
| 4 | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82373.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 649.5 | |
| All* | Total formula weight | 83022.5 |
