6E1M
Structure of AtTPC1(DDE) reconstituted in saposin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Two pore calcium channel protein 1 | polymer | 727 | 84547.2 | 2 | UniProt (Q94KI8) Pfam (PF00520) | Arabidopsis thaliana (Mouse-ear cress) | Calcium channel protein 1,AtCCH1,Fatty acid oxygenation up-regulated protein 2,Voltage-dependent calcium channel protein TPC1,AtTPC1 |
| 2 | C, D, E, F, G... (A, B) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 3 | H, I, J, K, L... (A, B) | PALMITIC ACID | non-polymer | 256.4 | 14 | Chemie (PLM) | |||
| 4 | O, Y (A, B) | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE | non-polymer | 705.0 | 2 | Chemie (3PH) | |||
| 5 | AA, Z (B, A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B: 12 - 733 (UniProt: Q94KI8)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | initiating methionine |
| Asn 240 | Asp 240 | engineered mutation |
| Asn 454 | Asp 454 | engineered mutation |
| Gln 528 | Glu 528 | engineered mutation |
| Leu 734 | - | expression tag |
| Val 735 | - | expression tag |
| Pro 736 | - | expression tag |
| Arg 737 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 169094.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 5280.5 | |
| All* | Total formula weight | 174374.9 |
