6E1A
Menin bound to M-89
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Menin | polymer | 550 | 61061.2 | 1 | UniProt (O00255) Pfam (PF05053) | Homo sapiens (Human) | |
| 2 | B (A) | (1S,2R)-2-[(4S)-2-methyl-4-{1-[(1-{4-[(pyridin-4-yl)sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}-1,2,3,4-tetrahydroisoquinolin-4-yl]cyclopentyl methylcarbamate | non-polymer | 657.9 | 1 | Chemie (HL7) | |||
| 3 | C, D, E, F, G (A) | praseodymium triacetate | non-polymer | 318.0 | 5 | Chemie (7PR) | |||
| 4 | H (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 2 - 610 (UniProt: O00255)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| - | Arg 460 | deletion |
| - | Glu 461 | deletion |
| - | Ala 462 | deletion |
| - | Glu 463 | deletion |
| - | Ala 464 | deletion |
| - | Ala 465 | deletion |
| - | Glu 466 | deletion |
| - | Ala 467 | deletion |
| - | Glu 468 | deletion |
| - | Glu 469 | deletion |
| - | Pro 470 | deletion |
| - | Trp 471 | deletion |
| - | Gly 472 | deletion |
| - | Glu 473 | deletion |
| - | Glu 474 | deletion |
| - | Ala 475 | deletion |
| - | Arg 476 | deletion |
| - | Glu 477 | deletion |
| - | Gly 478 | deletion |
| - | Arg 479 | deletion |
| - | Arg 480 | deletion |
| - | Arg 481 | deletion |
| - | Gly 482 | deletion |
| - | Pro 483 | deletion |
| - | Arg 484 | deletion |
| - | Arg 485 | deletion |
| - | Glu 486 | deletion |
| - | Ser 487 | deletion |
| - | Lys 488 | deletion |
| - | Pro 489 | deletion |
| - | Glu 490 | deletion |
| - | Glu 491 | deletion |
| - | Pro 492 | deletion |
| - | Pro 493 | deletion |
| - | Pro 494 | deletion |
| - | Pro 495 | deletion |
| - | Lys 496 | deletion |
| - | Lys 497 | deletion |
| - | Pro 498 | deletion |
| - | Ala 499 | deletion |
| - | Leu 500 | deletion |
| - | Asp 501 | deletion |
| - | Lys 502 | deletion |
| - | Gly 503 | deletion |
| - | Leu 504 | deletion |
| - | Gly 505 | deletion |
| - | Thr 506 | deletion |
| - | Gly 507 | deletion |
| - | Gln 508 | deletion |
| - | Gly 509 | deletion |
| - | Ala 510 | deletion |
| - | Val 511 | deletion |
| - | Ser 512 | deletion |
| - | Gly 513 | deletion |
| - | Pro 514 | deletion |
| - | Pro 515 | deletion |
| - | Arg 516 | deletion |
| - | Lys 517 | deletion |
| - | Pro 518 | deletion |
| - | Pro 519 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61061.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2248.1 | |
| All* | Total formula weight | 63309.3 |
