6DVZ
Cryo-EM structure of mouse TRPV3-Y564A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 3 | polymer | 791 | 90615.4 | 4 | UniProt (Q8K424) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) | Mus musculus (Mouse) | TrpV3 |
| 2 | E, F, G, H, I... (A, B, C, D) | 2-aminoethyl diphenylborinate | non-polymer | 225.1 | 12 | Chemie (FZ4) |
Sequence modifications
A, B, C, D: 3 - 794 (UniProt: Q8K424)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ala 564 | Tyr 564 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 362461.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2701.1 | |
| All* | Total formula weight | 365162.8 |
