6DVR

Crystal structure of human CARM1 with (R)-SKI-72

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histone-arginine methyltransferase CARM1	polymer	344	38976.5	2	UniProt (Q86X55) Pfam (PF06325) Pfam (PF22528)	Homo sapiens (Human)	Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4
2	C, I (A, B)	(2R,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-methoxyphenyl)ethyl]hexanamide (non-preferred name)	non-polymer		618.7	2	Chemie (HDG)
3	D, J (A, B)	2,5,8,11,14,17-HEXAOXANONADECAN-19-OL	non-polymer		296.4	2	Chemie (P15)
4	E, F, G, H, K... (A, B)	UNKNOWN ATOM OR ION	non-polymer			6	Chemie (UNX)
5	M, N (A, B)	water	water		18.0	405	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77952.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1830.2
All*	Total formula weight	79783.1

*Water molecules are not included.