6DVO
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hdac6 protein | polymer | 364 | 40285.5 | 1 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) | Danio rerio (Zebrafish) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | E (A) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 5 | F (A) | 3-fluoro-N-hydroxy-4-[(methyl{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]methyl}amino)methyl]benzamide | non-polymer | 346.4 | 1 | Chemie (HBV) | |||
| 6 | G, H, I, J, K... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 7 | O (A) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: A7YT55)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40285.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1101.7 | |
| All* | Total formula weight | 41387.2 |
