6DVO
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hdac6 protein | polymer | 364 | 40285.5 | 1 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) In PDB | Danio rerio (Zebrafish) | |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
4 | A | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
5 | A | 3-fluoro-N-hydroxy-4-[(methyl{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]methyl}amino)methyl]benzamide | non-polymer | 346.4 | 1 | Chemie (HBV) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
7 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: A7YT55)
PDB | External Database | Details |
---|---|---|
Ser 435 | - | expression tag |
Asn 436 | - | expression tag |
Ala 437 | - | expression tag |
Gly 438 | - | expression tag |
Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40285.5 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1101.7 | |
All* | Total formula weight | 41387.2 |