6DUV
Crystal structure of the second bromodomain of human BRD4 in complex with MS417 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 4 | polymer | 112 | 13037.2 | 2 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | C, D, G (A, B) | methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate | non-polymer | 414.9 | 3 | Chemie (0S6) | |||
| 3 | E, F, H, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | M, N (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26074.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1679.2 | |
| All* | Total formula weight | 27753.5 |
