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6DU4

Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferasepolymer31335754.41UniProt (Q86W50)
Pfam (PF05971)
Homo sapiens (Human)Methyltransferase 10 domain-containing protein,Methyltransferase-like protein 16,N6-adenosine-methyltransferase METTL16
2B
(B)
hp1x-RNA (29-MER)polymer299401.71Homo sapiens
3C, D
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4E, F
(A, B)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
5G, H
(A, B)
waterwater18.0385Chemie (HOH)
Sequence modifications
A: 1 - 310 (UniProt: Q86W50)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45156.0
Non-Polymers*Number of molecules4
Total formula weight428.5
All*Total formula weight45584.5
*Water molecules are not included.

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PDB entries from 2026-01-14

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