6DTZ
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA primase large subunit | polymer | 201 | 23347.3 | 1 | UniProt (P20457) Pfam (PF04104) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | DNA polymerase alpha:primase complex p58 subunit,Pol alpha-primase complex p58 subunit,DNA primase 58 kDa subunit |
| 2 | B (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 3 | C, D (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | E (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 5 | F (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 316 - 512 (UniProt: P20457)
| PDB | External Database | Details |
|---|---|---|
| Gly 312 | - | expression tag |
| Pro 313 | - | expression tag |
| Gly 314 | - | expression tag |
| Ser 315 | - | expression tag |
| Phe 397 | Tyr 397 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23347.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 706.2 | |
| All* | Total formula weight | 24053.5 |
