6DTK
Heterodimers of FALS mutant SOD enzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, C, E, G, I) | Superoxide dismutase C111S/D83S-C111S HETERODIMER | polymer | 323 | 32725.1 | 5 | UniProt (P00441) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase 1,hSod1,Superoxide dismutase 1,hSod1 |
| 2 | F, H, J, L, N... (A, C, E, G, I) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 3 | G, I, K, M, O... (A, C, E, G, I) | COPPER (II) ION | non-polymer | 63.5 | 10 | Chemie (CU) | |||
| 4 | R (E) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 5 | AA, BA, CA, DA, EA (A, C, E, G, I) | water | water | 18.0 | 1356 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I: 0 - 153 (UniProt: P00441)
A, C, E, G, I: 170 - 322 (UniProt: P00441)
| PDB | External Database | Details |
|---|---|---|
| Ser 83 | Asp 84 | microheterogeneity |
| Ser 111 | Cys 112 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 154 | - | linker |
| Ala 155 | - | linker |
| Ala 156 | - | linker |
| Ala 157 | - | linker |
| Ser 158 | - | linker |
| Gly 159 | - | linker |
| Gly 160 | - | linker |
| Gly 161 | - | linker |
| Gly 162 | - | linker |
| Gly 163 | - | linker |
| Ser 164 | - | linker |
| Gly 165 | - | linker |
| Gly 166 | - | linker |
| Gly 167 | - | linker |
| Gly 168 | - | linker |
| Ser 169 | - | linker |
| Ser 252 | Asp 84 | microheterogeneity |
| Ser 280 | Cys 112 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 163625.6 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1391.6 | |
| All* | Total formula weight | 165017.2 |
