6DN8
SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | SPRY domain-containing SOCS box protein 4 | polymer | 229 | 25228.4 | 3 | UniProt (Q96A44) Pfam (PF00622) In PDB | Homo sapiens (human) | SSB-4 |
| 2 | B, D, F | (GZJ)VDINNN(CY3) Cyclic peptide inhibitor | polymer | 8 | 917.0 | 3 | BIRD (PRD_002312) | Homo sapiens | |
| 3 | A, C, E | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | A, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, C, E: 28 - 233 (UniProt: Q96A44)
| PDB | External Database | Details |
|---|---|---|
| Met 5 | - | initiating methionine |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Val 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Asn 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Tyr 23 | - | expression tag |
| Phe 24 | - | expression tag |
| Gln 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Met 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 78436.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 465.3 | |
| All* | Total formula weight | 78901.5 |
