6DN7

SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	SPRY domain-containing SOCS box protein 4	polymer	229	25228.4	2	UniProt (Q96A44) Pfam (PF00622)	Homo sapiens (Human)	SSB-4
2	B, D (B, D)	WDINNN(BAL) Cyclic peptide inhibitor	polymer	7	845.9	2	BIRD (PRD_002313)	Homo sapiens
3	E, F (A, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	G, H, I, J (A, B, C, D)	water	water		18.0	640	Chemie (HOH)

Sequence modifications

A, C: 28 - 233 (UniProt: Q96A44)

PDB	External Database	Details
Met 5	-	initiating methionine
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Ser 12	-	expression tag
Ser 13	-	expression tag
Gly 14	-	expression tag
Val 15	-	expression tag
Asp 16	-	expression tag
Leu 17	-	expression tag
Gly 18	-	expression tag
Thr 19	-	expression tag
Glu 20	-	expression tag
Asn 21	-	expression tag
Leu 22	-	expression tag
Tyr 23	-	expression tag
Phe 24	-	expression tag
Gln 25	-	expression tag
Ser 26	-	expression tag
Met 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	52148.5
Non-Polymers*	Number of molecules	2
	Total formula weight	70.9
All*	Total formula weight	52219.4

*Water molecules are not included.