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6DL7

Human mitochondrial ClpP in complex with ONC201 (TIC10)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
ATP-dependent Clp protease proteolytic subunit, mitochondrialpolymer22124179.97UniProt (Q16740)
Pfam (PF00574)
Homo sapiens (Human)Endopeptidase Clp
2H, I, J, K, L...
(A, B, C, D, E...)
7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-onenon-polymer384.57Chemie (ONC)
3O, P, Q, R, S...
(A, B, C, D, E...)
waterwater18.0753Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G: 58 - 277 (UniProt: Q16740)
PDBExternal DatabaseDetails
Ser 57-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight169259.1
Non-Polymers*Number of molecules7
Total formula weight2691.3
All*Total formula weight171950.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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