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6DL7

Human mitochondrial ClpP in complex with ONC201 (TIC10)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...ATP-dependent Clp protease proteolytic subunit, mitochondrialpolymer22124179.97UniProt (Q16740)
Pfam (PF00574)
In PDB
Homo sapiens (Human)Endopeptidase Clp
2A, B, C, D, E...7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-onenon-polymer384.57Chemie (ONC)
3waterwater18.0753Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G: 58 - 277 (UniProt: Q16740)
PDBExternal DatabaseDetails
Ser 57-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight169259.1
Non-Polymers*Number of molecules7
Total formula weight2691.3
All*Total formula weight171950.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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