6DI4
Rational Modification of Vanillin Derivatives to Stereospecifically Destabilize Sickle Hemoglobin Polymer Formation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | B, D (B, D) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | E, H, J, M (A, B, C, D) | CARBON MONOXIDE | non-polymer | 28.0 | 4 | Chemie (CMO) | |||
| 4 | F, I, K, N (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 5 | G, L (A, C) | {6-[(4-methoxy-2-methylphenoxy)methyl]pyridin-2-yl}methanol | non-polymer | 259.3 | 2 | Chemie (GJ1) | |||
| 6 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 784 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3096.6 | |
| All* | Total formula weight | 65177.7 |
