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6DHA

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27130997.02UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C, F
(A, B)
Hydroxy Pioglitazone (M-IV)non-polymer372.42Chemie (GFV)
3D, E
(A)
nonanoic acidnon-polymer158.22Chemie (KNA)
4G, H
(A, B)
waterwater18.0244Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61994.0
Non-Polymers*Number of molecules4
Total formula weight1061.4
All*Total formula weight63055.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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