6DF7

TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transcription initiation factor TFIID subunit	polymer	167	19302.5	2	UniProt (U3KMH2) Pfam (PF00439)	Oryctolagus cuniculus (Rabbit)
2	C, D (A, B)	6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one	non-polymer		431.5	2	Chemie (G9V)
3	E, F (A, B)	water	water		18.0	186	Chemie (HOH)

Sequence modifications

A, B: 1497 - 1638 (UniProt: U3KMH2)

PDB	External Database	Details
Met 1472	-	initiating methionine
His 1473	-	expression tag
His 1474	-	expression tag
His 1475	-	expression tag
His 1476	-	expression tag
His 1477	-	expression tag
His 1478	-	expression tag
Ala 1479	-	expression tag
Ser 1480	-	expression tag
Asp 1481	-	expression tag
Tyr 1482	-	expression tag
Lys 1483	-	expression tag
Asp 1484	-	expression tag
Asp 1485	-	expression tag
Asp 1486	-	expression tag
Asp 1487	-	expression tag
Lys 1488	-	expression tag
Gly 1489	-	expression tag
Ser 1490	-	expression tag
Leu 1491	-	expression tag
Val 1492	-	expression tag
Pro 1493	-	expression tag
Arg 1494	-	expression tag
Gly 1495	-	expression tag
Ser 1496	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38605.1
Non-Polymers*	Number of molecules	2
	Total formula weight	863.0
All*	Total formula weight	39468.1

*Water molecules are not included.