6DD3
Crystal structure of the double mutant (D52N/D407A) of NT5C2-537X in the active state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytosolic purine 5'-nucleotidase | polymer | 536 | 62010.7 | 1 | UniProt (P49902) Pfam (PF05761) | Homo sapiens (Human) | Cytosolic 5'-nucleotidase II |
| 2 | B, C, D, E (A) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | H (A) | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A: 1 - 536 (UniProt: P49902)
| PDB | External Database | Details |
|---|---|---|
| Asn 52 | Asp 52 | engineered mutation |
| Ala 407 | Asp 407 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62010.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 564.1 | |
| All* | Total formula weight | 62574.8 |
