6DC6
Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Ubiquitin-like modifier-activating enzyme 1 | polymer | 1015 | 113504.7 | 2 | UniProt (P22314) Pfam (PF00899) Pfam (PF16190) Pfam (PF16191) Pfam (PF10585) Pfam (PF09358) In PDB | Homo sapiens (Human) | Protein A1S9,Ubiquitin-activating enzyme E1 |
2 | B, D | Ubiquitin | polymer | 80 | 8907.2 | 2 | UniProt (P62979) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
3 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A, C | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) |
Sequence modifications
A, C: 49 - 1058 (UniProt: P22314)
B, D: 1 - 76 (UniProt: P62979)
PDB | External Database | Details |
---|---|---|
Gly 44 | - | expression tag |
Ala 45 | - | expression tag |
Met 46 | - | expression tag |
Gly 47 | - | expression tag |
Ser 48 | - | expression tag |
Ala 632 | Cys 632 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ala -2 | - | expression tag |
Met -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 244823.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 449.1 | |
All* | Total formula weight | 245273.0 |