6DC3
RSV prefusion F bound to RSD5 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Fab RSD5-Germline Heavy Chain | polymer | 230 | 24454.4 | 1 | UniProt (Q6N089) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (L) | Fab RSD5-Germline Light Chain | polymer | 216 | 22819.2 | 1 | UniProt (Q8N355) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (F) | RSV fusion glycoprotein | polymer | 568 | 63218.3 | 1 | UniProt (P03420) UniProt (M1E1E4) Pfam (PF00523) Pfam (PF07921) | Human respiratory syncytial virus A (strain A2) | Protein F |
| 4 | D, E, F, G, H... (H, L, F) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 5 | L, M (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
H: 1 - 102 (PDB: 6DC3)
H: 103 - 216 (UniProt: Q6N089)
L: 1 - 95 (PDB: 6DC3)
L: 96 - 213 (UniProt: Q8N355)
F: 1 - 513 (UniProt: P03420)
F: 518 - 545 (UniProt: M1E1E4)
F: 546 - 568 (PDB: 6DC3)
H: 103 - 216 (UniProt: Q6N089)
L: 1 - 95 (PDB: 6DC3)
L: 96 - 213 (UniProt: Q8N355)
F: 1 - 513 (UniProt: P03420)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Pro 102 | variant |
| Cys 155 | Ser 155 | engineered mutation |
| Phe 190 | Ser 190 | engineered mutation |
| Leu 207 | Val 207 | engineered mutation |
| Cys 290 | Ser 290 | engineered mutation |
| Val 379 | Ile 379 | variant |
| Val 447 | Met 447 | variant |
| Ser 514 | - | linker |
| Ala 515 | - | linker |
| Ile 516 | - | linker |
| Gly 517 | - | linker |
F: 546 - 568 (PDB: 6DC3)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 110491.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1691.2 | |
| All* | Total formula weight | 112183.1 |
